I had to defriend my first person on Facebook. It was my little sister. But I had good reasons. For starters, she updated her status about 6 gajillion times a day. And it was never anything interesting. It was always "doing dishes" or "why does this always happen to me" or "can't WAIT". And I know I can take that stuff off of my news feed, but that wasn't all. She also liked to make electronic holiday posters and tag all of her friends in it. So I would see a notification saying I'd been tagged in her photo. Then I'd go to the photo, and it would be a WordArt drawing of "Happy Holidays" and it would have 435 people tagged in it.
And it felt really good to defriend her. It was like taking out the trash after it's started to stink. Or like sitting down after being on your feet for a long time. It was such a relief. I think I might find more people to defriend. It's very freeing.